Copyright â 2015 by Springer-Verlag London
1: Basic Coronary Artery Anatomy and Histology
Origin from the Sinus of Valsalva
Left Anterior Descending Artery
2: Physiology of Coronary Blood Flow
Mechanical Determinants of Coronary Blood Flow
Coronary Artery Perfusion Pressure
Coronary Artery Resistance
Myocardial Oxygen Demand and Supply
Control of Coronary Flow and Autoregulation
Tachycardia and Bradycardia Effects on Coronary Flow
Pathophysiology of Coronary Artery Stenosis
Hemodynamic Significance of Coronary Stenosis
Assessing Significance of Coronary Stenosis
3: Pathophysiology of Coronary Artery Disease
Definition: Myocardial Infarction
Theories of Atherogenesis
Reaction to Injury Theory
Atherosclerosis: Pathophysiology
Microscopic Description of the Development of an Atherosclerotic Lesion
Macroscopic Description of the Development of an Atherosclerotic Lesion
Arterial Remodeling and Coronary Artery Disease
AHA Classification (Fig. 3.5)
Type III: The Intermediate Lesion
Coronary Artery Restenosis
4: Qualitative and Quantitative Coronary Angiography
Selective Coronary Angiography
Engagement of Right Coronary Artery Using Judkins Right Catheter (Femoral Approach)
Engagement of the Left Coronary Artery Using Judkins Left (JL) Catheter (Femoral Approach)
Engagement of the Left Coronary Artery Using Amplatz (Femoral)
Engagement of the Right Coronary Artery Using Amplatz (Femoral)
Cineangiographic Imaging, Radiation Dose Measurement, and Contrast Types
Radiation Dose Measurement
Angiographic Projections, Recommended Views for Specific Coronary Segments
Specific Coronary Segments
Recommended Views for Specific Coronary Segments
Circumflex and Marginal Branches
LAD and Diagonal Branches
LAD-Circumflex Bifurcation, Circumflex, Marginal
Left Anterior Descending (LAD)-Circumflex Bifurcation
Left Coronary Artery Bypass Graft Angiography
Right Coronary Bypass Graft Angiography
Left Internal Mammary Artery Graft Catheterization
Right Internal Mammary Artery Graft Catheterization
Wall Motion Abnormalities
Calculation of LV Ejection Fraction
Ventricular Septal Defect
Identifying Specific Coronary and Aortic Abnormalities
Coronary Artery Aneurysms (CAA)
Calcified Coronary Artery Plaque
Coronary Artery Dissection
Coronary Artery Tortuosity
Arteriovenous (AV) Fistula
Contrast Induced Nephropathy (CIN)
Coronary Artery Dissection
Coronary Artery Perforation
Additional Complications: Death, Stroke, Arrhythmias, and Heart Failure
Angiographic Evaluation of Coronary Perfusion
Quantitative Coronary Angiography (QCA)
Assessment of Lesions Characteristics and Suitability for PCI
Limitations of Coronary Angiography
5: Imaging of Coronary Artery Anomalies
Embryology of Coronary Artery Development
Classification of Anomalies
Anomalous Coronary Artery from the Opposite Sinus (ACAOS)
Anomalous Coronary Artery from the Pulmonary Artery, the Bland-White-Garland Syndrome
Imaging for Coronary Anomalies
Coronary CT Angiography (CTA)
Coronary Magnetic Resonance Angiography
Invasive Coronary Angiography
Screening for Coronary Anomalies
Management of Coronary Anomalies
6: Coronary Flow Resistance and Reserve
Background and Physiology
Relationship of Coronary Artery Resistance and Basal Coronary Blood Flow
Hyperemic Coronary Blood Flow
Measures of Resistance and Flow in the Cardiac Catheterization Laboratory
Assessing Coronary Indices of Flow and Resistance: Technique and Performance
Coronary Flow Reserve in Different Populations
7: Fractional Flow Reserve
Background and Physiology
Characteristics of Fractional Flow Reserve
Abnormal FFR Has a Well-defined Cutoff with a Narrow Grey Zone of 0.75–0.8
FFR Is Not Influenced by Systemic Hemodynamics
The Theoretical Normal FFR Value Is 1 Regardless of the Patient, the Vessel, and the Myocardial Bed
FFR Has Unparalleled Special Resolution
FFR Normalizes the Stenosis Severity to Myocardial Mass Being Perfused
FFRmyo Accounts for Both Antegrade and Retrograde (Collateral) Blood Flow
Artifacts, Pitfalls and Troubleshooting
Hyperemic Agents and Pharmacological Considerations
Hemodynamic Artifacts and Technical Considerations
Less Common Physiological FFR Artifacts
Hydrostatic Pressure Effect
Oscillation of the FFR Waveform
Severe Hypotension, Low Flow/Low Gradient Severe Stenosis, and Paradoxical Vasoconstrictive Response
Technique and Performance
Specific Lesion and Patient Subsets
Evaluation of Indeterminate Coronary Stenosis and Multivessel CAD
Combined Anatomic and Physiologic Lesion Assessment
Left Main Coronary Artery
False Positive FFR and False Negative FFR
8: Intravascular Ultrasound
Technique and Instrumentation
Non-uniform Rotational Distortion (NURD)
Assessment of Intermediate Non-left Main Coronary Lesions
Assessment of Left Main Stenosis
IVUS Guided Bare Metal Stent Placement
IVUS Guided Drug Eluting Stent Placement
IVUS Guided PCI in Unprotected LM Lesions
IVUS Guided PCI in Bifurcation Lesions
9: Optical Coherence Tomography
Optical Coherence Technology
Co-registration of Three-dimensional OCT and Cineangiography
Three-dimensional Visualization
Image Acquisition Protocols Using the FD OCT Catheter
Lesion and Stent Morphology by OCT
OCT Coronary Evaluation Prior to Percutaneous Coronary Intervention
Coronary Evaluation After Percutaneous Coronary Intervention
Strut Coverage, Restenosis, and Neoatherosclerosis
OCT for Vessel Sizing and Determination of Ischemia
OCT Versus IVUS Assessment of Coronary Artery Disease and Percutaneous Coronary Intervention Results
10: Intracoronary Imaging for Plaque Characterization
Plaque Characterization by IVUS
Attenuated Plaque by IVUS
Plaque Characterization by VH-IVUS
Plaque Characterization by OCT
Calcification and Fibrous Plaque by OCT
Lipid-Rich Plaque and OCT-Derived Thin Cap Fibroatheroma
Plaque Characterization by NIRS
NIRS Detects Lipid-Core Plaque
NIRS and Peri-procedural Myocardial Infarction
NIRS Findings at Culprit Sites in ACS
Quantifying Lipid-Core Plaque by NIRS
11: Intracoronary Imaging for PCI Planning and Stent Optimization
Intracoronary Imaging for PCI Planning
Assessing Lesions of Intermediate Stenosis Severity
Clinical Application of IVUS MLA in Non-left Main Locations
Measuring Target Lesion MLA
Clinical Application of IVUS MLA in the Left Main
Clinical Application of OCT MLA
Intracoronary Imaging for Stent Selection
Intracoronary Imaging to Assess the Risk of Peri-Procedural Myocardial Infarction and Angiographic No-Reflow
IVUS Predictors of Acute PCI-Related Complications
Periprocedural Infarction and No-Reflow
NIRS Predictors of Acute PCI-Related Complications
OCT Predictors of Acute PCI-Related Complications
Limitation of Using Intracoronary Imaging to Assess PCI Risk
Intracoronary Imaging for Stent Optimization
Stent Optimization with IVUS or OCT
Stent Strut Malapposition and Underexpansion
Clinical Benefit Associated with Intracoronary Imaging
Benefit of IVUS-Guided Bare-Metal Stent Placement
Benefit of IVUS-Guided Drug-Eluting Stent Placement
12: Non-invasive Correlation of Invasive Imaging
The Ideal Coronary Plaque Characterization Tool
Case 1. Stress Testing: Validity and Correlation
Case 2. Coronary Computed Tomographic Angiography: Accuracy of Disease Detection
Case 3. Unstable Coronary Plaque Detection by CTA
Case 4. CTA: Correlation to Advanced Coronary Imaging
13: Intra-cardiac Echocardiography-
Guided Interventional Imaging
AcuNav/Viewflex Fixed or Phased Array Echo Catheter
Ultra ICE Mechanical Echo Catheter
Long Axis View (Also Caval View)
Septal View (Also Called Atrial View)
Examples Using Intracardiac Echocardiography
Secundum Atrial Septal Defect Closure
Patent Foramen Ovale Closure
Percutaneous Balloon Mitral Valvuloplasty
ICE Guidance for Intracardiac Interventions
Mechanical Versus Phase Array Imaging and 3D Imaging
|